diff --git a/public/locales/en-GB/app.json b/public/locales/en-GB/app.json
index 7d4ae7b3..871567b8 100644
--- a/public/locales/en-GB/app.json
+++ b/public/locales/en-GB/app.json
@@ -42,6 +42,7 @@
   "Display name": "Display name",
   "Download debug logs": "Download debug logs",
   "Element Call Home": "Element Call Home",
+  "Single-key keyboard shortcuts": "Single-key keyboard shortcuts",
   "Entering room…": "Entering room…",
   "Exit full screen": "Exit full screen",
   "Fetching group call timed out.": "Fetching group call timed out.",
@@ -133,6 +134,7 @@
   "Walkie-talkie call": "Walkie-talkie call",
   "Walkie-talkie call name": "Walkie-talkie call name",
   "WebRTC is not supported or is being blocked in this browser.": "WebRTC is not supported or is being blocked in this browser.",
+  "Whether to enable single-key keyboard shortcuts, e.g. 'm' to mute/unmute the mic.": "Whether to enable single-key keyboard shortcuts, e.g. 'm' to mute/unmute the mic.",
   "Yes, join call": "Yes, join call",
   "You can't talk at the same time": "You can't talk at the same time",
   "Your recent calls": "Your recent calls"
diff --git a/src/config/Config.ts b/src/config/Config.ts
index 42d9b1b1..2806a5b0 100644
--- a/src/config/Config.ts
+++ b/src/config/Config.ts
@@ -14,7 +14,11 @@ See the License for the specific language governing permissions and
 limitations under the License.
 */
 
-import { DEFAULT_CONFIG, ConfigOptions, ResolvedConfigOptions } from "./ConfigOptions";
+import {
+  DEFAULT_CONFIG,
+  ConfigOptions,
+  ResolvedConfigOptions,
+} from "./ConfigOptions";
 
 export class Config {
   private static internalInstance: Config;
diff --git a/src/room/PTTButton.tsx b/src/room/PTTButton.tsx
index 3551cfa2..e083759b 100644
--- a/src/room/PTTButton.tsx
+++ b/src/room/PTTButton.tsx
@@ -23,6 +23,7 @@ import { ReactComponent as MicIcon } from "../icons/Mic.svg";
 import { useEventTarget } from "../useEvents";
 import { Avatar } from "../Avatar";
 import { usePrefersReducedMotion } from "../usePrefersReducedMotion";
+import { getSetting } from "../settings/useSetting";
 
 interface Props {
   enabled: boolean;
@@ -134,6 +135,12 @@ export const PTTButton: React.FC<Props> = ({
       (e: KeyboardEvent) => {
         if (e.code === "Space") {
           if (!enabled) return;
+          // Check if keyboard shortcuts are enabled
+          const keyboardShortcuts = getSetting("keyboard-shortcuts", true);
+          if (!keyboardShortcuts) {
+            return;
+          }
+
           e.preventDefault();
 
           hold();
@@ -148,6 +155,12 @@ export const PTTButton: React.FC<Props> = ({
     useCallback(
       (e: KeyboardEvent) => {
         if (e.code === "Space") {
+          // Check if keyboard shortcuts are enabled
+          const keyboardShortcuts = getSetting("keyboard-shortcuts", true);
+          if (!keyboardShortcuts) {
+            return;
+          }
+
           e.preventDefault();
 
           unhold();
diff --git a/src/room/useGroupCall.ts b/src/room/useGroupCall.ts
index 3a917f95..14e40d14 100644
--- a/src/room/useGroupCall.ts
+++ b/src/room/useGroupCall.ts
@@ -33,6 +33,8 @@ import { usePageUnload } from "./usePageUnload";
 import { PosthogAnalytics } from "../PosthogAnalytics";
 import { TranslatedError, translatedError } from "../TranslatedError";
 import { ElementWidgetActions, ScreenshareStartData, widget } from "../widget";
+import { getSetting } from "../settings/useSetting";
+import { useEventTarget } from "../useEvents";
 
 export interface UseGroupCallReturnType {
   state: GroupCallState;
@@ -298,11 +300,18 @@ export function useGroupCall(groupCall: GroupCall): UseGroupCallReturnType {
     PosthogAnalytics.instance.eventMuteCamera.track(toggleToMute);
   }, [groupCall]);
 
+  const setMicrophoneMuted = useCallback(
+    (setMuted) => {
+      groupCall.setMicrophoneMuted(setMuted);
+      PosthogAnalytics.instance.eventMuteMicrophone.track(setMuted);
+    },
+    [groupCall]
+  );
+
   const toggleMicrophoneMuted = useCallback(() => {
     const toggleToMute = !groupCall.isMicrophoneMuted();
-    groupCall.setMicrophoneMuted(toggleToMute);
-    PosthogAnalytics.instance.eventMuteMicrophone.track(toggleToMute);
-  }, [groupCall]);
+    setMicrophoneMuted(toggleToMute);
+  }, [groupCall, setMicrophoneMuted]);
 
   const toggleScreensharing = useCallback(async () => {
     if (!groupCall.isScreensharing()) {
@@ -395,6 +404,68 @@ export function useGroupCall(groupCall: GroupCall): UseGroupCallReturnType {
     }
   }, [t]);
 
+  const [spacebarHeld, setSpacebarHeld] = useState(false);
+
+  useEventTarget(
+    window,
+    "keydown",
+    useCallback(
+      (event: KeyboardEvent) => {
+        // Check if keyboard shortcuts are enabled
+        const keyboardShortcuts = getSetting("keyboard-shortcuts", true);
+        if (!keyboardShortcuts) {
+          return;
+        }
+
+        if (event.key === "m") {
+          toggleMicrophoneMuted();
+        } else if (event.key == "v") {
+          toggleLocalVideoMuted();
+        } else if (event.key === " ") {
+          setSpacebarHeld(true);
+          setMicrophoneMuted(false);
+        }
+      },
+      [
+        toggleLocalVideoMuted,
+        toggleMicrophoneMuted,
+        setMicrophoneMuted,
+        setSpacebarHeld,
+      ]
+    )
+  );
+
+  useEventTarget(
+    window,
+    "keyup",
+    useCallback(
+      (event: KeyboardEvent) => {
+        // Check if keyboard shortcuts are enabled
+        const keyboardShortcuts = getSetting("keyboard-shortcuts", true);
+        if (!keyboardShortcuts) {
+          return;
+        }
+
+        if (event.key === " ") {
+          setSpacebarHeld(false);
+          setMicrophoneMuted(true);
+        }
+      },
+      [setMicrophoneMuted, setSpacebarHeld]
+    )
+  );
+
+  useEventTarget(
+    window,
+    "blur",
+    useCallback(() => {
+      if (spacebarHeld) {
+        setSpacebarHeld(false);
+        setMicrophoneMuted(true);
+      }
+    }, [setMicrophoneMuted, setSpacebarHeld, spacebarHeld])
+  );
+
   return {
     state,
     calls,
diff --git a/src/settings/SettingsModal.tsx b/src/settings/SettingsModal.tsx
index f895538a..5bf02e78 100644
--- a/src/settings/SettingsModal.tsx
+++ b/src/settings/SettingsModal.tsx
@@ -28,6 +28,7 @@ import { ReactComponent as OverflowIcon } from "../icons/Overflow.svg";
 import { SelectInput } from "../input/SelectInput";
 import { useMediaHandler } from "./useMediaHandler";
 import {
+  useKeyboardShortcuts,
   useSpatialAudio,
   useShowInspector,
   useOptInAnalytics,
@@ -59,6 +60,7 @@ export const SettingsModal = (props: Props) => {
   const [spatialAudio, setSpatialAudio] = useSpatialAudio();
   const [showInspector, setShowInspector] = useShowInspector();
   const [optInAnalytics, setOptInAnalytics] = useOptInAnalytics();
+  const [keyboardShortcuts, setKeyboardShortcuts] = useKeyboardShortcuts();
 
   const downloadDebugLog = useDownloadDebugLog();
 
@@ -166,6 +168,20 @@ export const SettingsModal = (props: Props) => {
               }
             />
           </FieldRow>
+          <FieldRow>
+            <InputField
+              id="keyboardShortcuts"
+              label={t("Single-key keyboard shortcuts")}
+              type="checkbox"
+              checked={keyboardShortcuts}
+              description={t(
+                "Whether to enable single-key keyboard shortcuts, e.g. 'm' to mute/unmute the mic."
+              )}
+              onChange={(event: React.ChangeEvent<HTMLInputElement>) =>
+                setKeyboardShortcuts(event.target.checked)
+              }
+            />
+          </FieldRow>
         </TabItem>
         <TabItem
           title={
diff --git a/src/settings/useSetting.ts b/src/settings/useSetting.ts
index b6de9a21..7e52fe8a 100644
--- a/src/settings/useSetting.ts
+++ b/src/settings/useSetting.ts
@@ -61,3 +61,5 @@ export const getSetting = <T>(name: string, defaultValue: T): T => {
 export const useSpatialAudio = () => useSetting("spatial-audio", false);
 export const useShowInspector = () => useSetting("show-inspector", false);
 export const useOptInAnalytics = () => useSetting("opt-in-analytics", false);
+export const useKeyboardShortcuts = () =>
+  useSetting("keyboard-shortcuts", true);